One of the things I like about it is the real-time effects on your missions and assignments your decisions have.

[SPOILER ALERT]
For instance the mission on Peak 15 - if you try to get in the 'good' way by getting key cards, etc. you can still travel down to the quarantined lab and synthesize a cure for the toxin, whilst sneaking in through the maintenance access stirs up the rachni and does not allow you to return to the quarantine lab.
[/SPOILER]

I don't particularly like the inventory system however. It is extremely tedious to use as you get more items. And quite frankly, half of the armours and weapons are useless. What is nice is that you can convert useless items into Gel to repair your APC and open locks.

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